DENT HEALTH Medicated Toothpaste Series Relaunched for Total Care (Prevention of Periodontal Disease, Bleeding, and Bad Breath)

Lion Corporation (President and CEO: Masayuki Takemori) is relaunching its "DENT HEALTH" series of toothpastes for the prevention of periodontal disease. Targeting individuals who notice changes in their mouths, such as receding gums, and are looking for a toothpaste that can provide future prevention, the brand is renewing its message and packaging to offer a toothpaste for "total care of weakened gums and teeth, preventing periodontal disease, bleeding, and bad breath." Furthermore, for those who want to prevent periodontal disease by suppressing swelling and bleeding, we will launch the new "DENT HEALTH Medicated Toothpaste DX Double Anti-inflammatory Ingredients." For those who want to prevent multiple oral symptoms in addition to periodontal disease prevention, we will launch the new "DENT HEALTH Medicated Toothpaste DX Multi-Function in." Both will be newly released nationwide from October 2026.

- Common to the series, the maximum concentration of antibacterial ingredient IPMP and anti-inflammatory ingredient TXA (※1) is formulated for total periodontal disease care.

- Two anti-inflammatory ingredients comprehensively suppress gum inflammation. The new "DENT HEALTH Medicated Toothpaste DX Double Anti-inflammatory Ingredients" suppresses swelling and bleeding to prevent periodontal disease.

- The "DENT HEALTH Medicated Toothpaste DX" has been improved and enhanced with a new function to prevent hypersensitivity symptoms, in addition to preventing periodontal disease (※2) and cavities. The new "DENT HEALTH Medicated Toothpaste DX Multi-Function in" protects weakened gums and teeth with a multi-care formulation.

(※1) Within our company

(※2) General term for periodontal disease and gingivitis

1. Launch Objectives

In recent years, against the backdrop of the pandemic and growing interest in healthy life expectancy, self-management awareness has increased, with people wanting to "take care of themselves before problems occur." In the oral healthcare field, the rate of dental check-ups is also rising year by year. As more people objectively review their oral condition and notice changes in their teeth and gums, the need to "choose a more effective toothpaste that can prevent future risks" is growing (※3). Furthermore, with this improvement in oral care awareness, the "personalization of periodontal disease" is progressing, with people beginning to recognize periodontal disease as a common risk.

Therefore, we are relaunching the series for those who are becoming conscious of preventing periodontal disease. The new item, "DX Double Anti-inflammatory Ingredients," contains two anti-inflammatory ingredients to suppress gum inflammation and prevent periodontal disease. The improved product, "DX Multi-Function in," adds a new function to prevent hypersensitivity symptoms in addition to preventing periodontal disease (※2) and cavities, meeting a wider range of needs.

(※3) n=3,200, Web survey (conducted in May 2025)

2. Release Date and Region

DENT HEALTH Medicated Toothpaste DX Double Anti-inflammatory Ingredients: October 7, 2026 (Wed) Nationwide

DENT HEALTH Medicated Toothpaste DX Multi-Function in: Scheduled for natural transition in October 2026 Nationwide

3. Product Name, Capacity, and Price

Product Name

Capacity

Retail Price (MSRP)

DENT HEALTH Medicated Toothpaste

DX Double Anti-inflammatory Ingredients

(Quasi-drug)

Sales Name: DENT HEALTH Dental Paste Ra

28g, 85g

Open Price

DENT HEALTH Medicated Toothpaste

DX Multi-Function in

(Quasi-drug)

Sales Name: DENT HEALTH Dental Paste Ta

28g, 85g

Open Price

4. Product Features

"DENT HEALTH Medicated Toothpaste DX Double Anti-inflammatory Ingredients"

(1) Double anti-inflammatory ingredients comprehensively suppress gum inflammation. Suppresses swelling and bleeding, preventing periodontal disease.

- Tranexamic acid (TXA): Suppresses gum swelling and bleeding.

- Dipotassium Glycyrrhizate (GK2): Works on the cause of inflammation and suppresses inflammation.

(2) Total periodontal disease care (prevention of periodontal disease, bleeding, and bad breath).

- Antibacterial ingredient: Isopropyl methylphenol (IPMP) prevents gingivitis and bad breath.

- Anti-inflammatory ingredient: Tranexamic acid (TXA) suppresses gum swelling and bleeding, preventing periodontal disease.

- Gum activating ingredient: Vitamin E (Tocopheryl Acetate) promotes blood circulation in the gums, preventing periodontal disease.

(3) Maximum concentration of medicinal ingredients (IPMP, TXA) (※1).

(4) Contains astringent medicinal ingredient sodium chloride to tighten gums and prevent periodontal disease.

Contains the astringent medicinal ingredient sodium chloride. The formulation provides a feeling of tightening gums along with a moderate salty taste.

(5) High concentration fluorine 1450ppm (※4) prevents the onset and progression of cavities.

- Fluoride: Sodium Monofluorophosphate

(※4) Please refrain from using this product on children under 6 years of age.

(6) Medical Herb Mint flavor for thorough brushing.

The moderate salty taste and refreshing herb mint flavor create a pleasant sensation that makes daily brushing easy to continue.

"DENT HEALTH Medicated Toothpaste DX Multi-Function in"

(1) In addition to the DX toothpaste's formulation to protect weakened gums and teeth, it has "multi-functions" to prevent hypersensitivity symptoms.

- In addition to preventing periodontal disease (※2) and cavities, it newly incorporates a hypersensitivity symptom prevention function to "prevent tooth sensitivity."

- Formulated for those who prefer multi-care, wanting to prevent multiple symptoms with one product.

(2) Total periodontal disease care (prevention of periodontal disease, bleeding, and bad breath).

- Antibacterial ingredient: Isopropyl methylphenol (IPMP) prevents gingivitis and bad breath.

- Anti-inflammatory ingredient: Tranexamic acid (TXA) suppresses gum swelling and bleeding, preventing periodontal disease.

- Gum activating ingredient: Vitamin E (Tocopheryl Acetate) promotes blood circulation in the gums, preventing periodontal disease.

(3) Maximum concentration of medicinal ingredients (IPMP, TXA) (※1).

(4) "High-adhesion formulation" that adheres closely to gums and teeth.

This high-adhesion formulation is designed with a highly viscous gel paste that envelops weakened gums and teeth, allowing the medicinal ingredients to remain and act effectively.

(5) High concentration fluorine 1450ppm (※4) prevents the onset and progression of cavities.

- Fluoride: Sodium Fluoride

(6) Medicinal Clean Herb flavor with a sense of efficacy.

The clean herbal scent combines a sense of medicinal efficacy with ease of brushing.

5. DENT HEALTH Medicated Toothpaste Series Product Lineup

Below, underlined items are new products in this release. All are quasi-drugs.

From left:

DENT HEALTH Medicated Toothpaste Bad Breath Block (Sales Name: DENT HEALTH Dental Paste Ka) 28g/85g

DENT HEALTH Medicated Toothpaste Sensitivity Block (Sales Name: DENT HEALTH Dental Paste Ma) 85g

DENT HEALTH Medicated Toothpaste Unpolished Gel (Sales Name: DENT HEALTH Dental Paste Na) 85g

DENT HEALTH Medicated Toothpaste DX Double Anti-inflammatory Ingredients (Sales Name: DENT HEALTH Dental Paste Ra) 28g/85g

DENT HEALTH Medicated Toothpaste DX Multi-Function in (Sales Name: DENT HEALTH Dental Paste Ta) 28g/85g

DENT HEALTH Medicated Toothpaste DX Premium (Sales Name: DENT HEALTH Dental Paste Sa) 30g/90g

[Related Information]

- Integrated Report "Accelerating Growth in Oral Healthcare"

- Integrated Report "R&D and Intellectual Property Strategy"

- News Release "Total Care for Periodontal Disease by Enhancing Gum Repair Power* with New DENT HEALTH Medicated Toothpaste DX Premium"

* Medicinal ingredient Vitamin E (Tocopheryl Acetate) activates gum cells and repairs tissue.

August 4, 2025