[New Trends in Health and Productivity Management] Major Corporations Advance Health Management by Promoting "Behavioral Change" Using Genetic and Gut Microbiome Data

KEAN Health Inc. (Headquarters: Minato-ku, Tokyo; Representative Director: Keita Yamaji) develops and provides genetic testing and gut microbiome testing services. By comprehensively capturing both unchanging genetic factors and environmental factors that shift based on lifestyle habits, the company supports health and productivity management optimized for each individual.

Our company has begun supporting the implementation of the "chatFLORA G" gut microbiome test for J-POWER Business Service Co., Ltd., a company selected for the "Health & Productivity Management Outstanding Organization Recognition Program (Large Enterprise Category)" for five consecutive years, to assist in their efforts to utilize employee health as a management resource.

This project is a follow-up to the 2025 fiscal year implementation of the "chatGENE Pro" genetic test, which allowed employees to understand their physical predispositions. The new initiative monitors the gut environment as a next step. We provide continuous support for lifestyle improvements by addressing both fixed elements (genetic predisposition) and changeable elements (gut environment). The program is designed not merely to present test results, but to leverage data to drive actual behavioral change.

Background: The Evolution of Health and Productivity Management Health and productivity management is evolving beyond simple employee welfare, moving toward a stage where it is positioned as a core management strategy. In recent years, there has been a shift away from uniform, one-size-fits-all measures toward individualized, data-driven health support.

J-POWER Business Service has implemented various health-related initiatives, such as seminars and health screenings, based on the belief that "employees working in a healthy and vibrant manner is directly linked to service quality and customer satisfaction." However, because these initiatives were primarily conducted at the headquarters, participation was skewed toward employees working in the headquarters area, creating a challenge in expanding the reach of these programs to local offices.

By introducing home-based personal testing, the company has transformed a situation where physical constraints created disparities in participation opportunities into a system where all employees can participate fairly, regardless of their location.

Phase 1 Results: Visualization of "Invariable Elements" through Genetic Testing With the "chatGENE Pro" genetic test introduced in fiscal year 2024, employees were able to grasp their own physical predispositions as data, leading to a deeper awareness of their health issues.

The main results are as follows:

Significant Improvement in Participation Rate While past initiatives saw only a small number of participants, more than half of the employees signed up for the genetic test, with 443 people participating.

Changes in Health Awareness Approximately 85% of respondents felt an "improvement in health awareness," and about 84% answered that it contributed to an "improvement in well-being awareness." *Survey respondents: 176 people

Creation of Concrete Behavioral Changes Participants reported autonomous behavioral changes based on their genetic data, such as "I learned that exercise is more effective for me than dietary restrictions, so I made using the stairs a habit" and "I started cutting back on salt and fat intake."

These results demonstrate that data-based individual approaches, rather than uniform health measures, are effective means of eliciting spontaneous employee action.

Phase 2: Monitoring "Variable Elements" through Gut Microbiome Testing This implementation marks a transition from the stage of "knowing one's inherent constitution" to the practical stage of "understanding one's current condition and connecting it to improvement."

Employees who have already identified their genetic traits—which do not change significantly throughout their lives—can now regularly check their gut environment, which changes based on diet, enabling more specific health-building efforts. In particular, for employees at local offices who tend to have irregular lifestyles, or for those struggling with changes in physical condition, we provide specific dietary advice based on test results to support the creation of a state where they can work stably.

The gut environment has been reported to be linked to fatigue, sleep, and mental health, and is attracting attention as an area that can also lead to improvements in presenteeism.

<Implementation Overview> ・Period: From March 2026 ・Target: Up to 360 employees of J-POWER Business Service (voluntary participation) ・Project Flow: 1. Updating self-understanding based on genetic test data (2025) 2. Visualization of the gut environment through gut microbiome testing 3. Implementation of lifestyle improvements based on analysis results

Comment from Mr. Kurahashi, General Affairs Department, J-POWER Business Service "Regardless of whether it was related to health management, we often heard from employees that they couldn't participate in various events because they were busy with regular work or because they worked at local offices."

"The 'genetic test' conducted in fiscal year 2024 could be done easily at home, so we had an unprecedented number of participants. We heard many happy comments, such as 'I was a bit hesitant to do it at my own expense, so I'm glad the company provided it as a policy' and 'It sparked great conversations with colleagues and family.'"

"In fiscal year 2025, we are stepping up from 'knowing one's genetic predisposition' to the theme of 'knowing one's current condition and connecting it to improvement' by conducting 'gut microbiome testing.' We have yet to compile the survey results from after the implementation, but I am looking forward to hearing the feedback."

"We would like to continue considering initiatives that our employees will appreciate."

Future Outlook KEAN Health will continue to evolve health and productivity management from "visualization" to "behavioral change" through our unique approach of comprehensively capturing both invariable and variable elements, centered on genetic and gut microbiome data. We will continue to contribute to corporate human capital management through data-based, individually optimized health support.

▼ Health and Productivity Management Site https://keanhealth.jp/lp?u=chatgene-hema

About KEAN Health Inc. More than 20 years have passed since the completion of the Human Genome Project, which decoded the entire human genome. As the concept of "Bio-Transformation"—where the evolution of biotechnology contributes to solving social issues and sustainable economic growth, fundamentally transforming society itself—gains attention, we are developing our business with the vision of creating a society where genomes and genes, which were once used primarily by researchers and other experts, become more accessible to the general public.