Notice Regarding Change in Management Structure

We hereby announce that our company will change its management structure effective April 1, 2026, as follows.

1. Change in Management Structure

Our company will change its management structure effective April 1, 2026, for the purpose of clearly separating the roles of supervision and execution and further strengthening corporate governance.

With this change, we aim to strengthen the supervisory function of the Board of Directors by inviting outside directors who have highly specialized expertise in management analysis and governance and are well-versed in the domestic and international pharmaceutical and healthcare industries.

At the same time, we will introduce an executive officer system and delegate the authority of the President and Executive Officer to the unit heads of the business and corporate divisions, thereby realizing faster decision-making and clearer roles and responsibilities.

2. Board of Directors Structure (Effective April 1, 2026)

Name

Title

Keiko Oishi

Representative Director

Shunji Katayama

Director

Kazutaka Echigo

Director

Eriko Kawai

Outside Director

Christopher Alberney

Outside Director

Stephen Engen

Outside Director

Wataru Mochizuki

Auditor

3. Executive Officer Structure (Effective April 1, 2026)

Name

Title

Keiko Oishi

President and Executive Officer

Kazutaka Echigo

Senior Executive Officer, Corporate Unit, Group Finance & Accounting

Kenji Hamaura

Senior Executive Officer, CMIC CMO Co., Ltd.

Hisao Matsubara

Senior Executive Officer, Corporate Unit

Akihisa Mitake

Senior Executive Officer, Healthcare Solution Unit

Akiyoshi Okuda

Senior Executive Officer, CRO & Consulting Unit

Hiroshi Kosaku

Senior Executive Officer, Strategic Business Unit

Kohei Sakazaki

Executive Officer, CMIC Healthcare Institute Co., Ltd.

Tomokazu Hasegawa

Executive Officer, CMIC Healthcare Institute Co., Ltd.

Takahiro Natsume

Executive Officer, Non-clinical Business

Ai Hara

Executive Officer, Orphan Pacific, Inc.

Megumi Kasai

Executive Officer, CMIC Career

Tomoko Goto

Executive Officer, Strategic Business Unit

Nakoto Sakurai

Executive Officer, Group HR

Shinji Ono

Executive Officer, Corporate Strategy and Planning

Kohei Morooka

Executive Officer, President's Office