Announcement of the Establishment of CareNet Clinical Research Operations Co., Ltd. (Abbreviation: CCRO)

CareNet Co., Ltd. (Headquarters: Chiyoda-ku, Tokyo; Representative Director and President: Katsuhiro Fujii; hereinafter "the Company")'s consolidated subsidiaries, Clayce Co., Ltd. (hereinafter "Clayce") and Satt Co., Ltd. (hereinafter "Satt"), completed an absorption-type merger (hereinafter "this merger") on April 1, 2026, with Clayce as the surviving company and Satt as the dissolved company.

Simultaneously, we are pleased to announce that the trade name of Clayce, the surviving company, was changed to "CareNet Clinical Research Operations Co., Ltd. (Abbreviation: CCRO)" on the same date. We will leverage the expertise cultivated by both companies and CareNet's physician member and media platform to the fullest extent to promote advanced CRO services that cover everything from clinical development to clinical research.

## 1. Background and Purpose of Organizational Restructuring

Our group, centered on "Healthcare x IT," is committed to realizing better healthcare by providing high-quality information and services to medical professionals and pharmaceutical companies. Amidst the accelerating digitalization in the pharmaceutical industry and changes in the environment surrounding clinical development and clinical research, we decided to proceed with this merger based on the policy of integrating management resources within the group to establish a more prompt and robust support system.

By integrating the expertise of Clayce, which has strengths in clinical development, and Satt, which has a track record in clinical research, we aim to provide higher value-added solutions to pharmaceutical companies and medical institutions.

## 2. Overview of the Integrated New Company

* **Trade Name:** CareNet Clinical Research Operations Co., Ltd. (Abbreviation: CCRO)
* **Location:** Capital Akasaka Building 6F, 1-7-19 Akasaka, Minato-ku, Tokyo
* **Representative:** Representative Director Norito Kawasaki
* **Capital:** 15 million yen
* **Business Activities:**
* Contracted clinical development operations, human resource dispatch, consulting on planning and implementation of clinical development (domestic clinical trials)
* Contracted clinical research operations, consulting on planning and implementation of clinical research
* Subject recruitment support
* **Licenses/Registrations:**
* Worker Dispatching Business License Number: 派13-306875
* Paid Employment Placement Business License Number: 13-ユ309033

## 3. Response to Business Partners

There will be no changes to existing contracts with business partners, services provided, or contact points due to this merger. While building upon existing trust, we will strive to further improve the quality of our services under the new structure.

## 4. Future Outlook

Through the new company "CCRO," the Company will promote the integrated and efficient development of solutions in both clinical development and clinical research. The group will continue to work together to flexibly respond to changes in the environment surrounding pharmaceutical development and contribute to the realization of better healthcare.

We ask for your continued guidance and encouragement.

## ◆ About CareNet

The CareNet Group, guided by the purpose "To support medical professionals and drive the future of medicine with knowledge, passion, and action," operates its business based on "CareNet.com," which boasts 240,000 physician members. We widely provide specialized services in the medical and pharmaceutical fields, ranging from medical human resources, education, and management to new drug development, clinical trials, and dissemination support.