A Clear Roadmap for Depression Care: 'Japan Society of Mood Disorders Depression Treatment Guidelines 2025' Released on June 15

Cover image of 'Japan Society of Mood Disorders Depression Treatment Guidelines 2025'

Igaku-Shoin Co., Ltd. (Headquarters: Bunkyo-ku, Tokyo; President and CEO: Shun Kanahara) has published the 'Japan Society of Mood Disorders Depression Treatment Guidelines 2025' (Supervised by: Japan Society of Mood Disorders; Edited by: Depression Treatment Guidelines Development Working Group) on June 15, 2026.

A Guideline Fully Rebuilt from Scratch

Since the first edition in 2012, the Japan Society of Mood Disorders has continuously revised the 'Japan Society of Mood Disorders Treatment Guidelines II. Major Depressive Disorder,' incorporating the latest findings and clinical needs. However, in recent years, international standards have increasingly emphasized scientific validity, transparency, and systematic rigor in the development process of clinical practice guidelines.

In response to this context, the Japan Society of Mood Disorders has completely rebuilt the guideline from the ground up, publishing the first full revision, the 'Depression Treatment Guidelines 2025.' This publication follows the 'Minds Clinical Practice Guideline Development Manual' by the Japanese Council for Quality Health Care, systematically evaluating evidence through systematic reviews and providing recommendations based on a balanced assessment of benefits and harms.

Supporting Depression Care with a Clinically Relevant Structure

This guideline emphasizes practical clinical problem setting, aiming for a structure that aligns with real-world clinical needs. Each chapter begins with a BQ (Background Question) that poses a clinically relevant inquiry—'What should be considered when implementing this treatment?'—followed by CQs (Clinical Questions) that include summaries of systematic reviews and additional literature deemed clinically significant.

Through extensive use of charts, tables, and flowcharts, the guideline is designed to serve as a navigational map, enabling readers to align its content with their own clinical challenges and avoid confusion in the complex landscape of depression treatment.

By establishing independent chapters based on life stages such as childhood/adolescence, perinatal period, and elderly; subtypes including severity, sleep disorders, and specific diagnostic terms introduced in DSM-5; and treatment phases, the guideline achieves a higher level of individualized clinical support.

Additionally, topics that are clinically important but not suitable for systematic review formats are included as 'Topics,' anticipating future clinical application.

Table of Contents

Chapter 1: Formulation of Treatment Plans

Chapter 2: Mild Depression

Chapter 3: Moderate to Severe Depression

Chapter 4: Depression in Children and Adolescents

Chapter 5: Perinatal Depression

Chapter 6: Depression in the Elderly

Chapter 7: Specific Diagnostic Terms

Chapter 8: Depression with Insomnia Symptoms

Chapter 9: Subsequent Treatment

Chapter 10: Further Stages of Treatment

Chapter 11: Maintenance Phase Treatment

Topics

Bibliographic Information

Title

Japan Society of Mood Disorders Depression Treatment Guidelines 2025

Supervised by

Japan Society of Mood Disorders

Edited by

Depression Treatment Guidelines Development Working Group

Publication Month

June 2026

Format

B5

Pages

296

Price

6,930 JPY (6,300 JPY + 10% tax)

ISBN

978-4-260-06533-7

Publisher

Igaku-Shoin

Details and Sample Text

https://www.igaku-shoin.co.jp/book/detail/118285

Inquiries

Please use the inquiry form on our website

https://www.igaku-shoin.co.jp/inquiry/books

About Igaku-Shoin Co., Ltd.

Since its founding in 1944, Igaku-Shoin has been committed to its mission: 'Recognizing the role and responsibility of a specialized publisher, we accurately deliver essential medical and healthcare information to contribute to medical advancement and societal welfare.' The company publishes a wide range of specialized books and journals, including the annual treatment compendium 'Today's Treatment Guidelines' and the textbook series 'Systematic Nursing Science Lectures' for nursing students, releasing over a hundred titles annually. In recent years, it has expanded into various content formats such as web distribution services, e-books, digital magazines, seminars, and owned media, earning strong support from medical professionals and students nationwide.

Company Overview

Company Name: Igaku-Shoin Co., Ltd. Founded: 1944

Representative: President and CEO Shun Kanahara

Headquarters: 1-28-23 Hongo, Bunkyo-ku, Tokyo Business: Publishing specialized books, journals, and digital media in medicine, nursing, and related fields

URL: https://www.igaku-shoin.co.jp/