PhenoAI Japan and St. Marianna University Launch 'Future Health Supporter Project (HPP Japan)' in the Tokyo Metropolitan Area, Using AI to Analyze Health Data and Build the Future of Preventive Medicine

PhenoAI Japan Inc. (Headquarters: Shibuya-ku, Tokyo; CEO: Hidetomo Otake) has partnered with St. Marianna University School of Medicine (Location: Miyamae-ku, Kawasaki City, Kanagawa Prefecture; Chairman: Katsuya Akashi; Dean: Hiroaki Kitagawa) to launch the Japanese version of the global health data research initiative, the 'Human Phenotype Project® (HPP)'—the 'Future Health Supporter Project (HPP Japan, hereinafter HPP Japan)'—in the Tokyo metropolitan area.

The St. Marianna University Institute of Breast and Imaging Advanced Medicine Clinic (Director: Mamoru Fukuda), which boasts advanced medical research infrastructure and extensive clinical experience, will serve as the hub for data collection and analysis, with both parties jointly advancing clinical research.

Accordingly, starting June 17, recruitment will begin for 'Future Health Supporters'—participants who contribute their health data to help advance future medicine. Participation allows individuals to gain deeper insights into their own health through detailed test data not available in standard health checkups, while also contributing to the progress of future medical science.

Overview of the 'Future Health Supporter Project (HPP Japan)'

The 'Future Health Supporter Project (HPP Japan)' is the Japanese adaptation of the 'Human Phenotype Project (HPP)', a global health research initiative originated from Israel's Weizmann Institute of Science.

HPP is a global project that aims to predict diseases, enable early detection, and realize personalized medicine by collecting and analyzing biological data from healthy individuals over the long term and from multiple angles. By using AI to analyze diverse data such as genomics, gut microbiota, and lifestyle habits, HPP seeks to detect subtle changes before illness occurs—changes previously invisible to traditional medicine—and ultimately build a society where people can live healthily throughout their lives.

The Future Health Supporter Project will conduct tests at St. Marianna University's facilities targeting individuals aged 40 to 69, collecting and analyzing multidimensional biological data—including blood, urine, stool, genome, gut microbiota, and continuous glucose monitoring—to uncover disease onset mechanisms and achieve disease prediction and prevention.

About Future Health Supporters

HPP Japan is recruiting 'Future Health Supporters' who share the vision of a world where people can live healthily for 100 years. By analyzing the vast amount of data collected from participants, the project aims to generate new scientific insights into human health and life that were previously unknown, contributing to the advancement of future medicine. The project aims to register 1,000 participants in Japan by 2026, expanding recruitment from Kawasaki and the Tokyo metropolitan area through partnerships with local governments, corporations, and medical institutions.

① Significance of Being a Future Health Supporter

Receiving long-term, detailed test result reports not available in standard health checkups By participating in the tests, individuals will receive special reports on post-meal blood glucose fluctuations, gut microbiota composition, and other insights not typically available in routine health screenings.

Continuously monitoring your own health data Tests will be conducted every two years, enabling participants to continuously track changes in their bodies over time.

※ Currently, the project has received ethical review board approval for five years, with plans to apply for continuous renewal and a maximum implementation period of 25 years.

Contributing to the future of medicine The biological samples and information provided will be used in data analysis and research leveraging cutting-edge medical technologies and AI, contributing to future medical advancements. This will enable the development of personalized prevention and treatment methods tailored to individual characteristics.

② Registration and Testing Facilities

Future Health Supporters will be invited to participate in tests conducted at the state-of-the-art St. Marianna University Institute B&I Center Clinic. For details on eligibility, registration methods, and test content, please visit the official website below.

Official website: https://www.hpp-japan.jp/

Comments on the Project Launch

Dr. Yoshihisa Yamanokuchi, Dean of Graduate School / Professor and Chair of Neurology, St. Marianna University School of Medicine

The Asao Ward of Kawasaki City, where the St. Marianna University Breast & Imaging Center is based, is Japan's top region for longevity. I believe the key to unlocking this mystery lies within the Future Health Supporter Project (HPP Japan).

As a neurologist, I have long treated patients with stroke and Alzheimer's disease, and I have deeply felt the limitations and realities of treating diseases only after they occur. Just as genomic medicine took 20 years to become widespread, I believe the next 20 years will usher in the era of 'phenotypic medicine.' The fact that we are now building this valuable data asset in Japan is profoundly fulfilling as a physician.

For those who participate, I hope they cherish the opportunity to access health data about themselves that cannot be obtained through standard checkups. I would be delighted if you would join us—for your own sake, and for the sake of future generations.

Hidetomo Otake, CEO, PhenoAI Japan Inc.

Rather than 'treating illness after it occurs,' we aim for 'preventing illness before it starts.' The Future Health Supporter Project (HPP Japan) is an initiative to realize this transformation through the power of data. With this collaboration with St. Marianna University, which possesses advanced medical capabilities and extensive clinical experience, a new testing hub has been established in the Tokyo metropolitan area. Long-term, multidimensional data accumulation is essential for disease prediction and early detection. We believe this partnership marks a significant step toward building a highly reliable foundation.

We are delighted to work together with our 'Future Health Supporters' to shape the future of preventive medicine in Japan and around the world, while helping individuals better understand their own health.

About PhenoAI Japan Inc.

PhenoAI Japan Inc. is the Japanese arm of the global cohort study 'Human Phenotype Project (HPP)', originated from Israel's Weizmann Institute of Science. HPP is a research project that aims to predict, prevent, and realize personalized medicine by collecting and analyzing lifestyle and biological data from healthy individuals over the long term. In Japan, the 'Future Health Supporter Project (HPP Japan)' began its cohort in March 2025. The company is collecting multidimensional health data from healthy individuals aged 40–69 and building a high-precision AI-powered analysis platform.

URL: https://www.phenoai.jp/

About St. Marianna University School of Medicine

Founded in 1971, St. Marianna University School of Medicine upholds the philosophy of cultivating physicians who are aware of the sanctity of life rooted in Christian human love, dedicated to serving humanity, and capable of applying specialized research outcomes to human welfare. The university, its affiliated hospitals, and research institutes work in close collaboration to elucidate the pathogenesis of intractable diseases, develop new diagnostic, therapeutic, and preventive methods, and advance clinical research and data science. By integrating accumulated clinical knowledge, research infrastructure, and human resources, the university aims to extend healthy life expectancy in Japan's super-aging society and translate research outcomes