Paper authored by Ryosuke Suzuki, embryologist at Kanagawa Ladies Clinic, published in Journal of Mammalian Ova Research
A paper authored by Ryosuke Suzuki, an embryologist at Kanagawa Ladies Clinic, which receives management support from SBC Medical Group Holdings, has been published in the academic journal "Journal of Mammalian Ova Research" (Vol.43 No.1, 2026) by the Japan Society for Ova Research. This paper summarizes the latest methods and practical innovations in "embryo cryopreservation," a crucial aspect of infertility treatment. It is expected to contribute to improving pregnancy rates and reducing patient burden through its application in clinical settings.
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- 📰 Published: May 11, 2026 at 20:00
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The paper "Freezing and Thawing Protocols and Practical Innovations for Human Cleavage-Stage Embryos and Blastocysts," authored by Ryosuke Suzuki, an embryologist at Kanagawa Ladies Clinic, which receives management support from SBC Medical Group Holdings (Location: California, USA; CEO: Yoshinori Aikawa), has been published in the academic journal "Journal of Mammalian Ova Research" (Vol.43 No.1, 2026), issued by the Japan Society for Ova Research. This paper summarizes the latest methods and practical innovations in "embryo cryopreservation*1," which is crucial in infertility treatment. It is expected to contribute to improving pregnancy rates and reducing patient burden through its application in clinical settings.
In infertility treatment, the technology of cryopreserving fertilized eggs (embryos) has become indispensable. Advances in this technology have made it possible to reduce the risk of multiple pregnancies and avoid complications such as Ovarian Hyperstimulation Syndrome (OHSS)*2. Furthermore, returning frozen embryos to the uterus at an appropriate time is said to lead to an improvement in the success rate of pregnancy.
This paper systematically organizes the practical innovations implemented daily at Kanagawa Ladies Clinic, based on the methods of the freezing and thawing kit called "Ready to Vitri/Warm Kit." In addition, it touches upon simpler protocols reported in recent years, also indicating the importance for each medical institution to select a method suitable for its own facility. The results of this research are expected to contribute to improving pregnancy rates in infertility treatment and alleviating the physical, mental, and economic burden on patients, through the dissemination of safe and effective freezing and thawing techniques.
In the rapidly advancing medical field, in addition to clinical practice, the sharing of specialized knowledge and academic collaboration are becoming increasingly important. To meet diversifying needs, it is essential to not only introduce cutting-edge technology but also to undertake initiatives based on a broad perspective and flexible thinking. SBC Medical Group will continue to promote advanced initiatives through academic activities and collaboration with research institutions, striving to improve medical safety and transparency and create sustainable value.
*1 Embryo cryopreservation: A technology to freeze fertilized eggs once and thaw them to return to the uterus at an appropriate time.
*2 Ovarian Hyperstimulation Syndrome (OHSS): A complication where ovaries overreact to ovulation-inducing drugs, leading to ascites or pleural effusion.
Paper Publication Overview
Journal: Journal of Mammalian Ova Research (Journal of the Japan Society for Ova Research)
Volume and Issue: Vol.43 No.1, pp.3-12, 2026
Paper Title: Freezing and Thawing Protocols and Practical Innovations for Human Cleavage-Stage Embryos and Blastocysts
Kanagawa Ladies Clinic
Kanagawa Ladies Clinic is an infertility treatment and in vitro fertilization specialized clinic based in Yokohama, Kanagawa Prefecture. With the motto "A clinic that is easy to access, convenient, and patient-friendly," it provides treatment tailored to each patient's condition and life stage. It offers a wide range of services from general infertility treatment to advanced reproductive medicine such as in vitro fertilization and embryo transfer, operating under a highly specialized medical system. In addition, it strives to provide medical care that aims to reduce patients' physical, mental, and economic burdens by considering ease of access and efficiency of the consultation process.
Official Website: https://www.klc.jp/
SBC Medical Group Holdings
SBC Medical Group Holdings is a Medical Services Organization that provides management support to medical institutions domestically and internationally across a wide range of medical fields, including advanced aesthetic medicine, dermatology, orthopedics, infertility treatment, gynecology, dentistry, alopecia treatment (AGA), and ophthalmology. It boasts diverse clinic brands and is expanding globally into medical tourism and the US/Asia markets. It was listed on NASDAQ in September 2024 and selected for the US stock index "Russell 3000" in June 2025. Moving forward, the group will continue to promote the provision of highly reliable medical services and network expansion to achieve its group purpose of "contributing to the improvement of 'happiness' for people worldwide through medical innovation."
English Name: SBC Medical Group Holdings Incorporated
Listing Market: NASDAQ Global Market
Ticker (US Stock Code): SBC
Location: 200 Spectrum Center Drive Suite 300 Irvine, CA 92618 USA
CEO: Yoshinori Aikawa
Business: Management support for medical institutions (aesthetic medicine, dermatology, orthopedics, infertility treatment, gynecology, dentistry, alopecia treatment (AGA), ophthalmology, etc.)
In infertility treatment, the technology of cryopreserving fertilized eggs (embryos) has become indispensable. Advances in this technology have made it possible to reduce the risk of multiple pregnancies and avoid complications such as Ovarian Hyperstimulation Syndrome (OHSS)*2. Furthermore, returning frozen embryos to the uterus at an appropriate time is said to lead to an improvement in the success rate of pregnancy.
This paper systematically organizes the practical innovations implemented daily at Kanagawa Ladies Clinic, based on the methods of the freezing and thawing kit called "Ready to Vitri/Warm Kit." In addition, it touches upon simpler protocols reported in recent years, also indicating the importance for each medical institution to select a method suitable for its own facility. The results of this research are expected to contribute to improving pregnancy rates in infertility treatment and alleviating the physical, mental, and economic burden on patients, through the dissemination of safe and effective freezing and thawing techniques.
In the rapidly advancing medical field, in addition to clinical practice, the sharing of specialized knowledge and academic collaboration are becoming increasingly important. To meet diversifying needs, it is essential to not only introduce cutting-edge technology but also to undertake initiatives based on a broad perspective and flexible thinking. SBC Medical Group will continue to promote advanced initiatives through academic activities and collaboration with research institutions, striving to improve medical safety and transparency and create sustainable value.
*1 Embryo cryopreservation: A technology to freeze fertilized eggs once and thaw them to return to the uterus at an appropriate time.
*2 Ovarian Hyperstimulation Syndrome (OHSS): A complication where ovaries overreact to ovulation-inducing drugs, leading to ascites or pleural effusion.
Paper Publication Overview
Journal: Journal of Mammalian Ova Research (Journal of the Japan Society for Ova Research)
Volume and Issue: Vol.43 No.1, pp.3-12, 2026
Paper Title: Freezing and Thawing Protocols and Practical Innovations for Human Cleavage-Stage Embryos and Blastocysts
Kanagawa Ladies Clinic
Kanagawa Ladies Clinic is an infertility treatment and in vitro fertilization specialized clinic based in Yokohama, Kanagawa Prefecture. With the motto "A clinic that is easy to access, convenient, and patient-friendly," it provides treatment tailored to each patient's condition and life stage. It offers a wide range of services from general infertility treatment to advanced reproductive medicine such as in vitro fertilization and embryo transfer, operating under a highly specialized medical system. In addition, it strives to provide medical care that aims to reduce patients' physical, mental, and economic burdens by considering ease of access and efficiency of the consultation process.
Official Website: https://www.klc.jp/
SBC Medical Group Holdings
SBC Medical Group Holdings is a Medical Services Organization that provides management support to medical institutions domestically and internationally across a wide range of medical fields, including advanced aesthetic medicine, dermatology, orthopedics, infertility treatment, gynecology, dentistry, alopecia treatment (AGA), and ophthalmology. It boasts diverse clinic brands and is expanding globally into medical tourism and the US/Asia markets. It was listed on NASDAQ in September 2024 and selected for the US stock index "Russell 3000" in June 2025. Moving forward, the group will continue to promote the provision of highly reliable medical services and network expansion to achieve its group purpose of "contributing to the improvement of 'happiness' for people worldwide through medical innovation."
English Name: SBC Medical Group Holdings Incorporated
Listing Market: NASDAQ Global Market
Ticker (US Stock Code): SBC
Location: 200 Spectrum Center Drive Suite 300 Irvine, CA 92618 USA
CEO: Yoshinori Aikawa
Business: Management support for medical institutions (aesthetic medicine, dermatology, orthopedics, infertility treatment, gynecology, dentistry, alopecia treatment (AGA), ophthalmology, etc.)