Launch of "enisie GLOW PACK FUTURE," Formulated with "iPSF®," an Ingredient Derived from iPS Cell Research

Available for sale starting Monday, April 6, 2026

Rhythm Co., Ltd. (Headquarters: Osaka City, Osaka Prefecture; Representative Director: Makoto Okumura), developer and provider of the skincare brand "enisie series," will launch "enisie GLOW PACK FUTURE" as an aesthetic salon-exclusive product on April 6, 2026, as part of the enisie GLOW PACK series.

[New Ingredient "iPSF®*1" Inspired by iPS Cell Research Included for the First Time in the Series]

"enisie GLOW PACK FUTURE" is an aesthetic salon-exclusive carbon dioxide pack that incorporates the new ingredient "iPSF®*1" for the first time in the enisie GLOW PACK series.

The primary feature is the inclusion of "iPSF®," a new ingredient that applies insights gained from the cultivation process of iPS cell research. Furthermore, by combining "ATP (Adenosine Triphosphate)" to support bouncy firmness, "Bakuchiol" to lead to a tightened skin appearance, and "Glutathione" to create a clear, translucent look*2, we have completed an advanced carbon dioxide pack worthy of the name "FUTURE."

While maintaining the core power of carbon dioxide and the comfortable usage experience of the series, it leads to a skin impression filled with firmness and moisture.

*1 Human (Fibroblast/Mononuclear Cell) Induced Pluripotent Stem Cell Conditioned Culture Media (Skin conditioning ingredient) *2 Impression due to moisture *All ingredients in this product (iPSF®, ATP, Bakuchiol, Glutathione, etc.) are formulated as skin conditioning ingredients.

[About the New Ingredient "iPSF®"] Applying Insights from iPS Cell Technology Highlighted in Cutting-Edge Bio-Research

"iPSF®" is a skin conditioning ingredient that utilizes the supernatant of culture media obtained during the iPS cell cultivation process. It is said to contain a well-balanced blend of ingredients to keep skin healthy, including various peptides containing growth factors and cytokines, as well as exosomes and amino acids.

These ingredients penetrate to the stratum corneum, conditioning the skin environment that tends to be disrupted by external factors such as dryness. It approaches concerns like lack of firmness and dryness from multiple angles, leading to a fresh, bouncy skin impression.

iPSF®, which applies the knowledge of advanced science, brings a tangible response to daily skincare.

*This product is a facial gel pack formulated with the supernatant of culture media from iPS cell cultivation. It does not contain iPS cells themselves. Furthermore, this product does not create iPS cells. *All ingredients are formulated for skin conditioning and moisturizing purposes. It does not indicate efficacy or effects like pharmaceuticals. There are individual differences in effects and usage experience.

[About the enisie Series]

The "enisie series" is a skincare brand that makes maximum use of the power of carbon dioxide based on the unique concept of regulating "skin rhythm."

In particular, the "GLOW PACK" has earned deep trust, primarily among aesthetic salons nationwide, as a pioneer of carbon dioxide packs. It continues to be chosen by many beauty enthusiasts for its professional-use quality.

[Product Information] enisie GLOW PACK FUTURE 7 applications: 16,100 yen (17,710 yen including tax)

<Set Contents> [Agent 1] Powder 4g x 7 packets [Agent 2] Gel 40g x 7 packets 1 Spatula

[Launch Information] Available from Monday, April 6, 2026 *Aesthetic salon-exclusive product

[Company Overview] Company Name: Rhythm Co., Ltd. Address: Dojima River Forum 3F, 1-1-12 Fukushima, Fukushima-ku, Osaka City, Osaka 553-0003 Representative: Makoto Okumura URL: https://rhythm-rhythm.co.jp/ Business Description: Wholesale of cosmetics and beauty products, beauty consulting, mail-order sales of cosmetics, operation of aesthetic salons, ODM/OEM business