Long-selling "Bigansui" Medicated Lotion, known for "When you think of acne," collaborates again with TV anime "The Apothecary Diaries" due to overwhelming popularity! Limited edition newly drawn designs appear for a limited time!
Meishoku Cosmetics has announced a second collaboration between its long-selling "Bigansui" medicated lotion and the TV anime "The Apothecary Diaries." Limited edition bottles featuring the protagonist Maomao will be released in limited quantities on April 30, 2026, and sold at drugstores nationwide.
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- 📰 Published: April 30, 2026 at 20:00
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Creating a beautiful future for people and the planet, Meishoku Cosmetics Co., Ltd. (Headquarters: Osaka, Osaka; Representative Director, Chairman and President: Seiichiro Momotani) of the Momotani Juntenkan Group, will launch a second collaboration design for its long-selling "Meishoku Bigansui Medicated Lotion" which has been loved since its launch in 1885 (Meiji 18), featuring Maomao, the protagonist of the TV anime "The Apothecary Diaries" on April 30, 2026.
©Natsu Hyuuga・Imagica Infos / "The Apothecary Diaries" Production Committee
TV Anime "The Apothecary Diaries" × Bigansui Collaboration Limited Package 2nd Edition Appears!
The special collaboration between "Bigansui," a historic lotion loved for 140 years since the Meiji era, and the TV anime "The Apothecary Diaries" has been realized again. For this project, newly drawn limited edition illustrations featuring attractive characters from the anime will be used for the package and label. The first collaboration was very well received by many customers and became a big topic, especially on SNS.
The TV anime "The Apothecary Diaries" is a highly popular work supported by a wide range of audiences, having won first place in the "Favorite Anime" ranking chosen by Generation Z*. The collaboration package brings together the world view of the work and the tradition of Bigansui, bringing out new appeal.
*Source: "Simeji" Gen Z's Top 10 Favorite Anime of 2023 (Baidu Japan Inc. survey) (https://prtimes.jp/main/html/rd/p/000000785.000006410.html)
【Product Overview】
"Meishoku Bigansui Medicated Lotion" is an acne care lotion born from the founder's love, "I want to make my wife, who suffers from acne, smile!" It treats acne with the effect of its double-active medicinal ingredients (salicylic acid and homosulfamine). It thoroughly removes old keratin clogged in pores, leaving skin clean and smooth! Salicylic acid is an active ingredient that softens old keratin that clogs pores and gently removes it. It also helps with acne scar care! Homosulfamine prevents the proliferation of acne bacteria, leading to skin that is less prone to acne. It can be used not only on the face but also on troublesome areas like the back and chest.
Point 1: Effect on Acne
Contains sterilizing, antibacterial, and anti-inflammatory ingredients to thoroughly remove the cause of acne! It prepares the skin to be less prone to acne.
Point 2: Effect on Pores
Removes keratin plugs and clogged pores, eliminating the cause of acne. It also cares for blackheads simultaneously.
Point 3: Effect on Shine
Suppresses excessive sebum secretion and prevents shine. Removes dirt and excess sebum to keep skin clean.
©Natsu Hyuuga・Imagica Infos / "The Apothecary Diaries" Production Committee
©Natsu Hyuuga・Imagica Infos / "The Apothecary Diaries" Production Committee
Product Name: Meishoku Bigansui The Apothecary Diaries Collaboration Design [Quasi-drug]
Selling Name: Meishoku Bigansui Medicated Lotion
Volume: 90mL
Price: 1,430 yen (tax included)
Sales Locations: National drugstores, etc.
*Some stores may not carry it.
●Official Brand Website
https://www.meishoku.co.jp/bigan/kusuriyanohitorigoto/
Recommended Usage
After washing your face, take an appropriate amount in your palm and gently apply it all over your face. If wiping, soak an appropriate amount on a cotton pad and wipe gently while pressing lightly. Please avoid leaving it on your face like a pack, as redness or other hypersensitivity symptoms may rarely occur.
History of Bigansui
"Nikibitori Bigansui," which was the trigger for our company's founding and the origin of the Bigan series, has been loved since its launch in 1885 (Meiji 18) until today. "Nikibitori Bigansui," created by the founder who wished for his wife suffering from acne to smile, is said to be the first lotion in Japan based on Western medicine.
About the TV anime "The Apothecary Diaries"
"The Apothecary Diaries," a hugely popular work with over 45 million copies sold in the series. The TV anime, which began broadcasting in October 2023, has garnered much sympathy for its thrilling heroine Maomao, authentic mystery, and human drama woven in an exotic world view, truly becoming a work loved by all ages and genders.
The 2nd anniversary of its broadcast will be celebrated on October 22, 2025, and the production of the 3rd season of the TV anime and the first theatrical film in the series has been announced. The 3rd season of the TV anime will be broadcast in two split cours starting from October 2026, and the theatrical film is scheduled to be released in December 2026.
Meishoku Cosmetics
Meishoku Cosmetics Co., Ltd. continues to develop products such as Keana Beaute, Moist Labo, and DET Clear, in addition to "Bigansui," which triggered the company's founding, as people age.
©Natsu Hyuuga・Imagica Infos / "The Apothecary Diaries" Production Committee
TV Anime "The Apothecary Diaries" × Bigansui Collaboration Limited Package 2nd Edition Appears!
The special collaboration between "Bigansui," a historic lotion loved for 140 years since the Meiji era, and the TV anime "The Apothecary Diaries" has been realized again. For this project, newly drawn limited edition illustrations featuring attractive characters from the anime will be used for the package and label. The first collaboration was very well received by many customers and became a big topic, especially on SNS.
The TV anime "The Apothecary Diaries" is a highly popular work supported by a wide range of audiences, having won first place in the "Favorite Anime" ranking chosen by Generation Z*. The collaboration package brings together the world view of the work and the tradition of Bigansui, bringing out new appeal.
*Source: "Simeji" Gen Z's Top 10 Favorite Anime of 2023 (Baidu Japan Inc. survey) (https://prtimes.jp/main/html/rd/p/000000785.000006410.html)
【Product Overview】
"Meishoku Bigansui Medicated Lotion" is an acne care lotion born from the founder's love, "I want to make my wife, who suffers from acne, smile!" It treats acne with the effect of its double-active medicinal ingredients (salicylic acid and homosulfamine). It thoroughly removes old keratin clogged in pores, leaving skin clean and smooth! Salicylic acid is an active ingredient that softens old keratin that clogs pores and gently removes it. It also helps with acne scar care! Homosulfamine prevents the proliferation of acne bacteria, leading to skin that is less prone to acne. It can be used not only on the face but also on troublesome areas like the back and chest.
Point 1: Effect on Acne
Contains sterilizing, antibacterial, and anti-inflammatory ingredients to thoroughly remove the cause of acne! It prepares the skin to be less prone to acne.
Point 2: Effect on Pores
Removes keratin plugs and clogged pores, eliminating the cause of acne. It also cares for blackheads simultaneously.
Point 3: Effect on Shine
Suppresses excessive sebum secretion and prevents shine. Removes dirt and excess sebum to keep skin clean.
©Natsu Hyuuga・Imagica Infos / "The Apothecary Diaries" Production Committee
©Natsu Hyuuga・Imagica Infos / "The Apothecary Diaries" Production Committee
Product Name: Meishoku Bigansui The Apothecary Diaries Collaboration Design [Quasi-drug]
Selling Name: Meishoku Bigansui Medicated Lotion
Volume: 90mL
Price: 1,430 yen (tax included)
Sales Locations: National drugstores, etc.
*Some stores may not carry it.
●Official Brand Website
https://www.meishoku.co.jp/bigan/kusuriyanohitorigoto/
Recommended Usage
After washing your face, take an appropriate amount in your palm and gently apply it all over your face. If wiping, soak an appropriate amount on a cotton pad and wipe gently while pressing lightly. Please avoid leaving it on your face like a pack, as redness or other hypersensitivity symptoms may rarely occur.
History of Bigansui
"Nikibitori Bigansui," which was the trigger for our company's founding and the origin of the Bigan series, has been loved since its launch in 1885 (Meiji 18) until today. "Nikibitori Bigansui," created by the founder who wished for his wife suffering from acne to smile, is said to be the first lotion in Japan based on Western medicine.
About the TV anime "The Apothecary Diaries"
"The Apothecary Diaries," a hugely popular work with over 45 million copies sold in the series. The TV anime, which began broadcasting in October 2023, has garnered much sympathy for its thrilling heroine Maomao, authentic mystery, and human drama woven in an exotic world view, truly becoming a work loved by all ages and genders.
The 2nd anniversary of its broadcast will be celebrated on October 22, 2025, and the production of the 3rd season of the TV anime and the first theatrical film in the series has been announced. The 3rd season of the TV anime will be broadcast in two split cours starting from October 2026, and the theatrical film is scheduled to be released in December 2026.
Meishoku Cosmetics
Meishoku Cosmetics Co., Ltd. continues to develop products such as Keana Beaute, Moist Labo, and DET Clear, in addition to "Bigansui," which triggered the company's founding, as people age.