Woman Develops Pustules After Childbirth, Doctor Treats with Precise Biological Agents for Gradual Recovery
The Dermatology Department of Dalin Tzuchi Hospital successfully treated a postpartum woman suffering from generalized pustular psoriasis caused by an IL-36 gene mutation. Using precise biological agents targeting the IL-36 inflammatory pathway, her symptoms were alleviated, and her quality of life significantly improved. This condition can be triggered by infections, medications, stress, and especially hormonal changes and increased stress after childbirth.
📋 Article Processing Timeline
- 📰 Published: April 29, 2026 at 18:26
- 🔍 Collected: April 29, 2026 at 18:31 (5 min after Published)
- 🤖 AI Analyzed: April 30, 2026 at 01:14 (6h 43m after Collected)
Central News Agency
(Central News Agency reporter Tsai Chih-min, Chiayi County, 29th) A woman developed pustules all over her body after childbirth and was referred to Dalin Tzuchi Hospital. Dr. Lin Teng-li, a dermatologist, diagnosed her with "generalized pustular psoriasis" due to an IL-36 gene mutation. After treatment with precise biological agents, her symptoms lessened, and she gradually returned to normal life.
Dalin Tzuchi Hospital announced today that Ms. Chen, 34, began to experience recurrent widespread red rashes and yellow-white pustules shortly after giving birth to her first child. The lesions spread from her waist and abdomen to her limbs, causing severe pain when sitting, standing, and dressing due to friction. Her condition did not improve for over a year, and she was eventually referred to the Dermatology Department of Dalin Tzuchi Hospital.
Dr. Lin Teng-li stated that during her initial visit, the patient had extensive yellow-white pustules all over her body, accompanied by large red patches and scaling at the base of the pustules. In addition to severe skin symptoms, she also experienced systemic discomforts such as fever, fatigue, and joint pain. Blood tests also showed significantly elevated white blood cell count, inflammatory markers, and liver function indices.
Dr. Lin said that genetic testing revealed the patient carried an IL-36 gene mutation, confirming a diagnosis of "generalized pustular psoriasis." The onset of this condition may be related to factors such as infection, medication, and stress. Postpartum women, in particular, are more susceptible to developing the disease due to hormonal changes and increased stress. Some patients also exhibit genetic abnormalities, especially mutations in IL-36-related genes.
Dr. Lin pointed out that the patient was initially misdiagnosed with eczema complicated by infection and was only referred to Dalin Tzuchi Hospital when her condition worsened. In the past, pustular psoriasis was often treated with oral retinoids, immunomodulatory drugs, and traditional biological agents, but with limited efficacy. With the advancement of precision medicine, new biological agents targeting the IL-36 inflammatory pathway have emerged, offering more effective and safer treatment options.
Dr. Lin emphasized that after confirming the patient's genetic abnormality, treatment with precise biological agents significantly reduced her red rashes and pustules, subsided her fever, and gradually restored her liver function indices to normal, greatly improving her quality of life.
Dr. Lin noted that in severe cases, generalized pustular psoriasis can even impair liver and kidney function, increase the risk of infection, sepsis, cardiovascular disease, and metabolic diseases, with a mortality rate of 10% to 15%. Patients should seek medical attention as soon as possible to avoid delaying treatment. (Editor: Lee Shu-hua) 1150429
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(Central News Agency reporter Tsai Chih-min, Chiayi County, 29th) A woman developed pustules all over her body after childbirth and was referred to Dalin Tzuchi Hospital. Dr. Lin Teng-li, a dermatologist, diagnosed her with "generalized pustular psoriasis" due to an IL-36 gene mutation. After treatment with precise biological agents, her symptoms lessened, and she gradually returned to normal life.
Dalin Tzuchi Hospital announced today that Ms. Chen, 34, began to experience recurrent widespread red rashes and yellow-white pustules shortly after giving birth to her first child. The lesions spread from her waist and abdomen to her limbs, causing severe pain when sitting, standing, and dressing due to friction. Her condition did not improve for over a year, and she was eventually referred to the Dermatology Department of Dalin Tzuchi Hospital.
Dr. Lin Teng-li stated that during her initial visit, the patient had extensive yellow-white pustules all over her body, accompanied by large red patches and scaling at the base of the pustules. In addition to severe skin symptoms, she also experienced systemic discomforts such as fever, fatigue, and joint pain. Blood tests also showed significantly elevated white blood cell count, inflammatory markers, and liver function indices.
Dr. Lin said that genetic testing revealed the patient carried an IL-36 gene mutation, confirming a diagnosis of "generalized pustular psoriasis." The onset of this condition may be related to factors such as infection, medication, and stress. Postpartum women, in particular, are more susceptible to developing the disease due to hormonal changes and increased stress. Some patients also exhibit genetic abnormalities, especially mutations in IL-36-related genes.
Dr. Lin pointed out that the patient was initially misdiagnosed with eczema complicated by infection and was only referred to Dalin Tzuchi Hospital when her condition worsened. In the past, pustular psoriasis was often treated with oral retinoids, immunomodulatory drugs, and traditional biological agents, but with limited efficacy. With the advancement of precision medicine, new biological agents targeting the IL-36 inflammatory pathway have emerged, offering more effective and safer treatment options.
Dr. Lin emphasized that after confirming the patient's genetic abnormality, treatment with precise biological agents significantly reduced her red rashes and pustules, subsided her fever, and gradually restored her liver function indices to normal, greatly improving her quality of life.
Dr. Lin noted that in severe cases, generalized pustular psoriasis can even impair liver and kidney function, increase the risk of infection, sepsis, cardiovascular disease, and metabolic diseases, with a mortality rate of 10% to 15%. Patients should seek medical attention as soon as possible to avoid delaying treatment. (Editor: Lee Shu-hua) 1150429
Choose to stand with facts, every sponsorship you make is a force for protecting press freedom.
Download Central News Agency's "First-hand News" APP to stay updated with the latest news.
The text, images, and audio/video on this website may not be reproduced, broadcast, or transmitted without authorization.