Rocket Grandpa Crosses into Biomedical Field: Aerospace Low-Temperature Plasma Aids Chronic Wound Treatment

National Yang Ming Chiao Tung University today issued a press release stating that plasma technology is widely used in the aerospace field, often for manufacturing coatings for rockets and satellites. Wu Jong-shinn, director of the National Space Organization and professor in the Department of Mechanical Engineering at Yang Ming Chiao Tung University, has been deeply involved in plasma technology for many years. His research team found that traditional plasma micro-nano bubble water mostly contains only oxygen-based active substances, which, despite having good bactericidal effects, have limitations in biomedical applications. To overcome this bottleneck, the team integrated years of plasma technology experience and pioneered the creation of "dual-mode dynamic plasma" by combining ozone-based oxygen-based active substances with nitric oxide-based nitrogen-based active substances, breaking through the physical limitations of single-gas products. Through system control, different ratios of oxygen-based and nitrogen-based free radicals can be generated and combined with micro-nano bubble water, which can be applied to the human body. The team's patented "dual-mode plasma micro-fine bubble water" forms a dual action mechanism of "first sterilization, then healing." It first inhibits pathogens with ozone and other oxygen-based free radicals, and then uses nitric oxide and other nitrogen-based free radicals to promote tissue repair and regeneration, achieving sterilization and repair in one go. It can be applied to chronic wounds that are difficult to heal for a long time, such as diabetic foot and bedsores, improving the quality of clinical care. In addition to wound care, this technology also has cross-disciplinary application potential, including skin disease treatment, medical aesthetics and health care, and high-standard food and agricultural product sterilization and cleaning, demonstrating the diverse development of plasma technology in biomedical and industrial applications. Yang Ming Chiao Tung University mentioned that this "dual-mode plasma micro-fine bubble water" patent is hailed as bringing "rocket-grade technology" back to Earth. Through cross-disciplinary integration, it has created a highly potential medical application direction. The team will continue to promote technology transfer and industry-academia cooperation to accelerate the application of biomedical plasma technology. (Editor: Chang Ming-kun) 1150407