NCU and NTUT Collaborate to Develop Green Process for Epinephrine Sensor

A research team from National Central University and National Taipei University of Technology in Taiwan has developed a highly sensitive epinephrine sensor using an eco-friendly green process with caffeic acid, promising advancements in medical diagnostics.
調査NQ 0/100出典:PR Times

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  • 📰 Published: April 16, 2026 at 11:38
  • 🔍 Collected: April 16, 2026 at 12:01 (22 min after Published)
  • 🤖 AI Analyzed: April 19, 2026 at 04:01 (63h 59m after Collected)
Central News Agency

(CNA Reporter Hsu Chih-wei, Taipei, 16th) A cross-disciplinary team from National Central University (NCU) and National Taipei University of Technology (NTUT) has collaborated to develop a green synthesis platform driven by caffeic acid. By embedding rhenium (Re) nanoparticles into self-templated double-shell zinc manganate hollow microspheres, they have constructed a highly sensitive electrochemical sensor for epinephrine.

NCU issued a press release today pointing out that epinephrine is an important neurotransmitter, and changes in its concentration are closely related to cardiovascular diseases and stress states. Developing an epinephrine electrochemical sensor with good sensitivity is of critical significance for clinical diagnosis and real-time monitoring.

Kung Tsun-hsiung, an associate professor at the Department of Electrical Engineering at NCU, collaborated with Chung Jen-chieh, a professor at the Department of Chemical Engineering at NTUT, to propose a novel green process. They prepared double-shell ZnMn₂O₄ (zinc manganate) hollow microspheres and then used the natural organic molecule "caffeic acid" as a reducing agent at room temperature to generate rhenium nanoparticles in situ and distribute them evenly on the surface of the material. This method avoids the use of traditional highly polluting reducing agents and conforms to the concept of green chemistry.

The research team explained that the introduction of rhenium nanoparticles did not destroy the original crystal structure of ZnMn₂O₄, and the material exhibited good mesoporous characteristics, which helped to improve electron transfer and interfacial reaction efficiency. In terms of sensing performance, it has a good linear relationship and reproducibility. In stability tests, it also demonstrated excellent long-term stability.

The research team stated that the key to this technology lies in combining the synergistic effect of the double-shell hollow structure and rhenium nanoparticles to simultaneously improve the material's conductivity, reactivity, and stability. This not only provides a new strategy for the integration of green nanomaterials and electrochemical sensing but also lays an important foundation for the future development of portable biomedical detection and real-time monitoring systems. (Editor: Wu Su-jou) 1150416

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