Controlling blood sugar in pre-diabetic stage can reduce mortality by 17%, study finds

(CNA, Taipei, May 31) Thinking that "slightly high blood sugar is fine" could mean missing a golden window for treatment. Research indicates that active blood sugar management during the pre-diabetic stage creates a "legacy effect," where early stability provides protection for decades, potentially reducing all-cause mortality by 17%. A systematic review published in the journal *Frontiers in Endocrinology* found that active intervention and monitoring in pre-diabetic patients not only delays deterioration but also reduces all-cause mortality by about 17% and the risk of retinopathy by 38% in populations without a history of cardiovascular disease. For those with a 10-year cardiovascular risk exceeding 10%, mortality could drop by 21%. Metabolic and weight loss specialist Dr. Chou Chien-an explained that this "legacy effect" means the body remembers the period of stability, protecting organs even if levels fluctuate later. Dr. Chou warned that pre-diabetes often has no symptoms and is easily ignored, but extreme diets are not the answer. He recommends check-ups every 3 to 6 months for high-risk groups, such as those with obesity, fatty liver, or family history. If HbA1c levels reach 5.7-6.4%, early intervention is crucial. Ideal management requires a comprehensive strategy involving professional assessment, medication, diet, and exercise.