Evolution to a Completely Anhydrous Formulation. High-Concentration*¹ Vitamin C*² Serum "C20" Renewed
Headspring Co., Ltd. is renewing its popular high-concentration vitamin C serum "C20" from the "CLEAR ZERO" pore care series of its medical-grade skincare brand "CLIGRAM" on May 1, 2026. The renewal features a completely anhydrous formulation, significantly improving stability while maintaining high efficacy and user comfort.
📋 Article Processing Timeline
- 📰 Published: May 7, 2026 at 19:00
- 🔍 Collected: May 7, 2026 at 10:31
- 🤖 AI Analyzed: May 7, 2026 at 12:07 (1h 35m after Collected)
Headspring Co., Ltd. (Location: Shinjuku-ku, Tokyo / Representative Director: Hiromi Saito) will renew and launch its popular vitamin C*² serum "C20" from the "CLEAR ZERO" pore care series of its medical-grade skincare brand "CLIGRAM" on Friday, May 1, 2026.
In recent years, high-concentration*¹ vitamin C*² products have been required to balance "perceived efficacy" with "stability" and "user experience." Against this backdrop of increasing demand, we have reviewed our formulation.
We approached the three challenges of "high concentration*¹ x stability x user experience" with our formulation technology.
[Renewal Points]
■ Refreshed to a completely anhydrous formulation, significantly improving vitamin C*² stability
This renewal completely eliminates water previously contained in the formulation, achieving an anhydrous formulation.
Pure vitamin C*² is an ingredient prone to oxidation and decomposition in the presence of water, but by making it anhydrous, these changes are suppressed.
As a result, it has evolved into a highly stable formulation that is less prone to discoloration even during long-term storage.
■ Maintaining high concentration*¹ of 20% and efficacy
The formulation maintains its highly effective concentration of 20% pure vitamin C*². The ability to address pores and rough skin remains the same, but it is now designed to deliver the ingredient to the skin in a more stable state.
■ Increased betaine to address irritation
To address the irritation often associated with high-concentration*¹ vitamin C*², we have significantly increased the amount of betaine, a moisturizing ingredient.
This updates the formulation to balance gentleness on the skin with ease of continued use.
[Product Outline]
Product name: C20 (Serum)
Launch date: Friday, May 1, 2026
Price: 6,820 yen (tax included)
Volume: 20mL (approx. 1-2 months' supply)
Product features:
Serum formulated with pure vitamin C*² at a high concentration*¹ of 20%.
It addresses visible pores and rough skin, leading to a smooth, bright, and clear complexion.
About the CLEAR ZERO series: A unique method that multi-facetedly approaches pore issues
"CLEAR ZERO" adopts a unique method called "Pore Reset Solution" that focuses on the root causes of pore problems.
Pore problems are not caused by a single factor, but by a complex interplay of multiple elements such as keratin, sebum, inflammation, oxidation, bacterial balance, and barrier function.
This series simultaneously addresses these six pore issues, providing care from the initial stages of skin problems and leading to a skin environment where recurrence is less likely.
By appropriately caring for pore clogging and inflammation and regulating the skin's rhythm in daily skincare, it aims to maintain a smooth and clear skin condition.
[Related Products]
■ AZA LOTION (Toner)
Price: 3,960 yen (tax included)
Volume: 120mL (approx. 1 month's supply)
Product features:
Formulated primarily with azelaic acid derivative*³ and skin-conditioning ingredients focused on sebum balance.
It multi-facetedly conditions the skin environment, leading to a stable complexion.
*Non-comedogenic tested (does not guarantee no acne for everyone)
■ AZA RESETTER (Cream)
Price: 4,620 yen (tax included)
Volume: 30g (approx. 1 month's supply)
Product features:
Balanced formulation of azelaic acid*⁴ and oil-soluble vitamin C derivative*⁵, etc.
It leads to smooth and lustrous skin for those concerned about rough skin and shine caused by dryness and sebum.
*Non-comedogenic tested (does not guarantee no acne for everyone)
*¹Compared to our existing products *²Ascorbic acid (skin conditioning ingredient) *³Azelaoyl diglycinate K (skin conditioning ingredient) *⁴Azelaic acid (skin conditioning ingredient) *⁵Ascorbyl tetraisopalmitate (skin conditioning ingredient)
About CLIGRAM
Cosmeceuticals that resonate with aesthetic medicine.
Based on the concept of "Evidence Based Cosmetics," it is a medical-grade high-concentration skincare series formulated with ingredients proven in medical institutions and highly sought-after ingredients at optimal concentrations based on clinical data.
By minimizing unnecessary components and selecting highly effective active ingredients at high concentrations in a simple formulation design, it aims for results in the shortest possible time.
We constantly strive for product development while keeping an eye on the forefront of aesthetic medicine, proposing a "Total Beauty Program" that links with aesthetic medicine to build beauty.
[CLIGRAM]
➤Official website: https://cligram.jp/
➤Inquiries here: https://cligram.jp/contact/
➤Official Instagram account: https://www.instagram.com/cligram_offi
In recent years, high-concentration*¹ vitamin C*² products have been required to balance "perceived efficacy" with "stability" and "user experience." Against this backdrop of increasing demand, we have reviewed our formulation.
We approached the three challenges of "high concentration*¹ x stability x user experience" with our formulation technology.
[Renewal Points]
■ Refreshed to a completely anhydrous formulation, significantly improving vitamin C*² stability
This renewal completely eliminates water previously contained in the formulation, achieving an anhydrous formulation.
Pure vitamin C*² is an ingredient prone to oxidation and decomposition in the presence of water, but by making it anhydrous, these changes are suppressed.
As a result, it has evolved into a highly stable formulation that is less prone to discoloration even during long-term storage.
■ Maintaining high concentration*¹ of 20% and efficacy
The formulation maintains its highly effective concentration of 20% pure vitamin C*². The ability to address pores and rough skin remains the same, but it is now designed to deliver the ingredient to the skin in a more stable state.
■ Increased betaine to address irritation
To address the irritation often associated with high-concentration*¹ vitamin C*², we have significantly increased the amount of betaine, a moisturizing ingredient.
This updates the formulation to balance gentleness on the skin with ease of continued use.
[Product Outline]
Product name: C20 (Serum)
Launch date: Friday, May 1, 2026
Price: 6,820 yen (tax included)
Volume: 20mL (approx. 1-2 months' supply)
Product features:
Serum formulated with pure vitamin C*² at a high concentration*¹ of 20%.
It addresses visible pores and rough skin, leading to a smooth, bright, and clear complexion.
About the CLEAR ZERO series: A unique method that multi-facetedly approaches pore issues
"CLEAR ZERO" adopts a unique method called "Pore Reset Solution" that focuses on the root causes of pore problems.
Pore problems are not caused by a single factor, but by a complex interplay of multiple elements such as keratin, sebum, inflammation, oxidation, bacterial balance, and barrier function.
This series simultaneously addresses these six pore issues, providing care from the initial stages of skin problems and leading to a skin environment where recurrence is less likely.
By appropriately caring for pore clogging and inflammation and regulating the skin's rhythm in daily skincare, it aims to maintain a smooth and clear skin condition.
[Related Products]
■ AZA LOTION (Toner)
Price: 3,960 yen (tax included)
Volume: 120mL (approx. 1 month's supply)
Product features:
Formulated primarily with azelaic acid derivative*³ and skin-conditioning ingredients focused on sebum balance.
It multi-facetedly conditions the skin environment, leading to a stable complexion.
*Non-comedogenic tested (does not guarantee no acne for everyone)
■ AZA RESETTER (Cream)
Price: 4,620 yen (tax included)
Volume: 30g (approx. 1 month's supply)
Product features:
Balanced formulation of azelaic acid*⁴ and oil-soluble vitamin C derivative*⁵, etc.
It leads to smooth and lustrous skin for those concerned about rough skin and shine caused by dryness and sebum.
*Non-comedogenic tested (does not guarantee no acne for everyone)
*¹Compared to our existing products *²Ascorbic acid (skin conditioning ingredient) *³Azelaoyl diglycinate K (skin conditioning ingredient) *⁴Azelaic acid (skin conditioning ingredient) *⁵Ascorbyl tetraisopalmitate (skin conditioning ingredient)
About CLIGRAM
Cosmeceuticals that resonate with aesthetic medicine.
Based on the concept of "Evidence Based Cosmetics," it is a medical-grade high-concentration skincare series formulated with ingredients proven in medical institutions and highly sought-after ingredients at optimal concentrations based on clinical data.
By minimizing unnecessary components and selecting highly effective active ingredients at high concentrations in a simple formulation design, it aims for results in the shortest possible time.
We constantly strive for product development while keeping an eye on the forefront of aesthetic medicine, proposing a "Total Beauty Program" that links with aesthetic medicine to build beauty.
[CLIGRAM]
➤Official website: https://cligram.jp/
➤Inquiries here: https://cligram.jp/contact/
➤Official Instagram account: https://www.instagram.com/cligram_offi