Tokushima University Discovers Mechanism Accelerating Autoimmune Diseases

德島大學研究發現免疫細胞與纖維母細胞的交互作用會加速自體免疫疾病惡化，阻斷該路徑有望成為開發新藥的標靶。
其他NQ 85/100出典：PR Times

📋 Article Processing Timeline

  • 📰 Published: May 16, 2026 at 00:00
  • 🔍 Collected: May 15, 2026 at 15:32
  • 🤖 AI Analyzed: May 15, 2026 at 18:40 (3h 7m after Collected)
Researchers at Tokushima University discovered a novel mechanism driving autoimmune diseases like Sjögren's syndrome. The interaction between CD153-expressing CD4+ T cells and CD30 receptors on fibroblasts amplifies chronic inflammation by inducing chemokine production. Blocking this CD153-CD30 pathway significantly suppresses tissue damage, offering a promising target for future drug development.

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